6-PYRAZOL-1-YL-NICOTINIC ACID METHYL ESTER

6-PYRAZOL-1-YL-NICOTINIC ACID METHYL ESTER - Names and Identifiers

Name	6-Pyrazol-1-yl-nicotinic acid methyl ester
Synonyms	Methyl 6-(1H-pyrazol-1-yl)nicotinate METHYL 6-(1H-PYRAZOL-1-YL)NICOTINATE 6-Pyrazol-1-yl-nicotinic acid methyl ester 6-PYRAZOL-1-YL-NICOTINIC ACID METHYL ESTER methyl 6-pyrazol-1-ylpyridine-3-carboxylate METHYL 6-(1H-PYRAZOL-1-YL)PYRIDINE-3-CARBOXYLATE methyl 6-(1H-pyrazol-1-yl)pyridine-3-carboxylate 6-(1-pyrazolyl)-3-pyridinecarboxylic acid methyl ester 3-pyridinecarboxylic acid, 6-(1H-pyrazol-1-yl)-, methyl ester 3-Pyridinecarboxylic acid, 6-(1H-pyrazol-1-yl)-, methyl ester
CAS	321533-62-4
InChI	InChI=1/C10H9N3O2/c1-15-10(14)8-3-4-9(11-7-8)13-6-2-5-12-13/h2-7H,1H3

6-PYRAZOL-1-YL-NICOTINIC ACID METHYL ESTER - Physico-chemical Properties

Molecular Formula	C10H9N3O2
Molar Mass	203.2
Density	1.27±0.1 g/cm3(Predicted)
Boling Point	330.8±27.0 °C(Predicted)
Flash Point	153.8°C
Vapor Presure	0.000163mmHg at 25°C
pKa	-0.42±0.19(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.613

6-PYRAZOL-1-YL-NICOTINIC ACID METHYL ESTER - Risk and Safety

Risk Codes	20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
Safety Description	S3/9 - S36/37 - Wear suitable protective clothing and gloves.
HS Code	29331990

6-PYRAZOL-1-YL-NICOTINIC ACID METHYL ESTER - Introduction

acid methyl ester is an organic compound with the chemical formula C10H9N3O2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: acid methyl ester is a colorless to pale yellow solid.
-Solubility: Soluble in organic solvents, such as ethanol and dichloromethane.
-Melting point: About 129-131 ° C.
-Stability: relatively stable at room temperature.

Use:
-acid methyl ester is a potential drug molecule that can be used in the field of medicinal chemistry research and drug development.
-It is used as an intermediate for the synthesis of other compounds, such as biologically active molecules.
-It can also be used as a catalyst in organic synthesis reactions.

Method:
-acid methyl ester can be obtained by synthetic reaction. A common synthetic method is through the condensation reaction of methylpyrazole-1-carboxylic acid with thionyl chloride as a primary amine (such as ethyldiphenylamine), it is then reacted with nicotinic acid to produce the target product.

Safety Information:
-the safety of acid methyl ester has not been fully evaluated and determined, so care should be taken when using and handling it.
-It may be irritating and damaging to the skin, eyes and respiratory system.
-Appropriate personal protective measures such as gloves, goggles and respiratory protective equipment should be taken during operation.
-It should be operated in a well-ventilated place and avoid inhalation or contact with its dust or vapor.
-Please refer to safety data sheets and other relevant safety information when using, storing and handling.

Last Update：2024-04-09 20:49:11